Rac-Nedisertib purogallin 1]heptan-3-yl]-5-methyl-1

1]heptan-3-yl]-5-methyl-1

InChiKey: FNGSQOJHNAYHAT-UHFFFAOYSA-N

It is a kind of ATR and P-gp inhibitor with high safety

a potent mGluR5 silent allosteric modulator (SAM)

CAS Number: 1249343-86-9

Rac-Nedisertib purogallin 1]heptan-3-yl]-5-methyl-1Rac Nedisertib (Rac M3814) is a racemate of Nedisertib, a potent DNA PK inhibitor, with an IC50 of <3 nM. DNA PK <3 nM (IC50) Rac Nedisertib (Compound 137) potently inhibits DNA PK, with an IC50 of <3 nM for DNA PK, 0. 5 5 M for cellular pDNA PK and 15 25 M for KV11. 1 (hERG, human ether a go go related gene) ).. . Thomas Fuchss, et al. Arylchinazoline. WO2014183850A1. Product information CAS Number: 1637542 34 7 Molecular Weight: 481. 91 Formula: