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PubMed PMID: 30799261
PMID: 30006065
10 μM) extends neurites in the retinal ganglion cells (RGCs) compared with those in RGCs treated without Y-39983
CAS Number: 1258275-73-8
Smiles: CC(C)C[C@H](NC(=O)[C@H]1O[C@@H]1C(O)=O)C(=O)NCCCCN=C(N)N
Dexpramipexole 60122 PubMed PMID: 30799261Dexpramipexole, also known as KNS 760704 and (R) Pramipexole, is under development for the treatment of amyotrophic lateral sclerosis (ALS), also known as Lou Gehrigs disease. The drug failed to show efficacy in terms of function or survival in a Phase III study of patients with ALS. Dexpramipexole is a low molecular weight, water soluble, orally bioavailable, renally excreted compound with linear pharmacokinetics, and has been shown to be well
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